Endocrine Abstracts

Background: Ophthalmopathic exophthalmos is reported to favourably regress after total thyroidectomy compared to radio-iodine or antithyroid drug therapy. In this context, we present our experience based on a surgical series of Graves’ disease.Materials and methods: This is a prospective study of 15 patients of Graves’ disease associated with ophthalmopathic exophthalmos. Preoperative and monthly postoperative evaluation of exophthalmos was don...

Introduction: One of the notable morbidity after total thyroidectomy is hypocalcemia related symptoms. Various treatments ranging from oral to parenteral calcium have been advocated. In this context, we analysed the benefits of bolus calcium vis-à-vis infusions for symptomatic post-thyroidectomy hypocalcemia.Patient and methods: The study was conducted in Endocrine Surgery Department in a teritiary care hospital. All the patients with benign thyroid...

Background: Hashimoto’s thyroiditis (HT) is the commonest cause of spontaneous hypothyroidism. We compared clinico-investigative profile between child HT vs adult HT.Material and methods: The study was conducted in Endocrine surgery department in a teritiary care hospital. The data was analyzed seperately for Group A: child HT (below 18 years) and Group B: adult (above 30 years).Results: The study period was 30 months (October...

Background: Dyshormonogenetic goiter and Hashimoto’s thyroiditis are amongst the commonest causes of hypothyroidism in children and adolescents Worldwide. But, the genetic basis and their hypothyroid phenotypes are under-reported, especially from developing countries. In this context, we screened for dyshormonogenetic mutations in hypothyroid children with dyshormogenetic goiter (DH) and Hashimoto’s thyroiditis (HT).Material and methods: In thi...

Introduction: Biliopancreatic diversion with duodenal switch (BPD DS) is the most effective metabolic surgery, but accounts for < 1% of metabolic surgeries performed Worldwide due to its technical complexity and severe malabsorption. Its loop modification, single anastomosis duodenoileal bypass with sleeve (SADI S) with 200–250 cm common channel, reduces malabsorption to some extent. But a 250 cm common channel appears to be shorter for Indian patients. &#8...

Case presentation: 73-year-old diabetic, hypertensive and alcoholic Male on treatment for type II diabetes for 25 years, underwent amputation of left great toe and second toe previously had sudden painless swelling of the left foot after a walk. He was diagnosed to have Charcot’s foot and had the appearance of bag of bones in CT scan. He was managed conservatively with immobilization and Custom made shoes.Discussion: Charcot foot is a sudden soften...

BackgroundThyroidectomy is the common most common endocrine surgical procedure varies from Scalpel to Robotic transoral thyroidectomy. Colloid nodules are common and easily operable without any difficulty. We report a phenomenon where in the surgery becomes difficult and lead to complications if not thought with this phenomenon – colloid leak.Material and methodThe endocrine surgeon (Associate Professor)...

Background: Diabetes mellitus is the commonest endocrinopathy, Worldwide. Inspite of its commonality, the genetic basis of etiopathogenesis and pathophysiology are ever evolving and enigmatic. Amongst the protean genetic variations, cubulin gene and megalin gene mutations in diabetes are important in dictating genotype—phenotypic correlations and natural clinical course of diabetes. The genetic studies in this area are especially very sparse from Indian sub-continent. In...

Introduction: Thyroidectomy can performed by open or wide array of endoscopic techniques. Lack of uniform consensus on specific indications for each technique leads to confusion on ideal thyroidectomy technique. In this context, we analysed our experience with specific emphasis on deducing an algorithm on ideal technique for a given patient. Material and methods: This is a retrospective study conducted at a tertiary care endocrine surgery department in S...

Background: Preeclampsia (PE) continues tochallenge both the clinicians and researchers worldwide, as the existing knowledge on its etiopathology does not come up with an efficient and foolproof treatment regime due its progressive nature and uncertain diagnosis and prognosis. In this context, miRNAs represent a potential therapeutic target and a diagnostic tool.Objectives: Circulating microRNAs present in maternal blood play an important role in the eti...